Guar gum

Biological properties


Gastrointestinal tract


Retards gastric emptying when used as a dietary fiber. The fiber decrease postprandial insulin levels, indicating a slowing down of glucose absorption [2]. Guar gum stimulate the growth of colonic microflora [3].


Antiviral activity


Inhibitor/Concentration (μg/mL) 200
Adsorption HSV-1 in Vero cells [5] 75
Adsorption HSV-2 in Vero cells [5] 90
Adsorption and replication HSV-1 in Vero cells [5] 75
Adsorption and replication HSV-2 in Vero cells [5] 85
Inhibition of virus multiplication in cells.


Cell line Concentration
Vero cells [5] 200
Maximal non-cytotoxic concentration (μg/ml).


Molecular biology


10-35% inhibition on the restriction enzyme HindIII at 100-500 μg polysaccharide / μg λ DNA [6].


Misc.


Guar gum reduces the level of serum lipids. Hydrolyzed guar gum also reduces serum lipid levels, but not as well as the guar gum. Especially the less volatile lipids like palm oil [4].

Hepatic levels of cholesterol and tricaylglycerol were lowered, but not the levels of phospholipids [4].

Guar gum increase the rate of bile flow [4].

Guar gum feeding increases the activity of 3-hydroxy-3-methylglutaryl-CoA reductase and cholesterol 7a-hydroxylase irrespectively of the dietary fat source [4].

No enhancement of lectin hemagglutinability [4].